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eclipse ti s inverted microscope  (Nikon)


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    Nikon eclipse ti s inverted microscope
    Eclipse Ti S Inverted Microscope, supplied by Nikon, used in various techniques. Bioz Stars score: 99/100, based on 57094 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/eclipse ti s inverted microscope/product/Nikon
    Average 99 stars, based on 57094 article reviews
    eclipse ti s inverted microscope - by Bioz Stars, 2026-06
    99/100 stars

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    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 <t>application.</t> <t>Whole-cell</t> recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis
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    Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis

    Journal: Purinergic Signalling

    Article Title: Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease

    doi: 10.1007/s11302-025-10127-1

    Figure Lengend Snippet: Testing inhibitory properties of SIL14 with patch-clamp. A Chemical structure of SIL14. B Representative current trace of pannexin-1 activity with 300 µM SIL14 application. Whole-cell recordings were obtained on CHO cells transiently transfected with mPanx1 under [90; −90] mV ramps. C Current–voltage characteristic of pannexin-1 conductance before and after SIL14 application. D Dose dependency of SIL14 effect on pannexin-1 measured at + 80 mV reveals IC 50 = 12.96 µM according to nonlinear regression analysis

    Article Snippet: For each patch-clamp experiment, a glass chip with cells was transferred into the chamber with a constant flow of bath solution, placed under the inverted microscope Nikon Ti-S. Whole-cell macroscopic current recordings of pannexin-1 were made under voltage-clamp conditions with ramp protocol (90- > −90 mV).

    Techniques: Patch Clamp, Activity Assay, Transfection